Raziskovalci Harvard Medical School in Technion-Israel Institute of Technology so posneli zelo zanimiv kratek film, v katerem so nazorno predstavili, kako postanejo bakterije odporne na antibiotike. Bakterije so izpostavili različnim koncentracijam antibiotika in dokumentirali, kako so počasi mutirale in postajale vse bolj odporne.
To observe how the bacterium Escherichia coli adapts to increasingly higher doses of antibiotics, researchers divided the dish into sections and saturated them with various doses of medication. The outermost rims of the dish were free of any drug. The next section contained a small amount of antibiotic—just above the minimum needed to kill the bacteria—and each subsequent section represented a 10-fold increase in dose, with the center of the dish containing 1,000 times as much antibiotic as the area with the lowest dose.
Over two weeks, a camera mounted on the ceiling above the dish took periodic snapshots that the researchers spliced into a time-lapsed montage. The result? A powerful, unvarnished visualization of bacterial movement, death and survival; evolution at work, visible to the naked eye.
(Vir: Bugs on Screen | HMS)
